Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase
Broad Institute · Howard Hughes Medical Institute · +6 more institutions
Abstract
No abstract available for this paper.
Citation impact
- FWCI
- 18.39
- Percentile
- 100%
- References
- 90
Authors
8- JRJason R. Cantor
Broad Institute, Howard Hughes Medical Institute, Allen Institute, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
- MAMonther Abu-Remaileh
Broad Institute, Howard Hughes Medical Institute, Allen Institute, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
- NKNaama Kanarek
Broad Institute, Howard Hughes Medical Institute, Allen Institute, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
- EFElizaveta Freinkman
Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
- XGXin Gao
Beth Israel Deaconess Medical Center, Harvard University, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology
Topics & keywords
- Biology
- Uric acid
- Metabolome
- Metabolite
- Endogeny
- Metabolism
- Biochemistry
- Pyrimidine metabolism
Funding
- UDU.S. Department of DefenseAward: W81XWH-15-1-0337
- AAAmerican Association for Cancer ResearchAward: 16-40-38-KANA
- ACAmerican Cancer SocietyAward: PF-12-099-01-TBG
- EMEuropean Molecular Biology OrganizationAwards: Long-Term Fellowship ALTF 350-2012, Long-Term Fellowship ALTF 1-2014
- KIKoch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
- NINational Institutes of HealthAwards: R01 CA103866, R37 AI047389