Stereodivergence in Asymmetric Catalysis

This Perspective presents an overview of catalytic enantioselective transformations that allow convenient access to all stereoisomers of a given product with multiple stereogenic centers. Particular focus is placed on discussion of the concept of stereodivergent dual catalysis and its application in target-oriented synthesis. The potential of this concept in the development of new transformations as well as implications for achieving stereochemical diversity in library design and diversity-oriented synthesis are also discussed.

• SN
  Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

  Award: 200020_152898
• ET
  Eidgenössische Technische Hochschule Zürich