Autonomous sweat extraction and analysis applied to cystic fibrosis and glucose monitoring using a fully integrated wearable platform

Perspiration-based wearable biosensors facilitate continuous monitoring of individuals' health states with real-time and molecular-level insight. The inherent inaccessibility of sweat in sedentary individuals in large volume (≥10 µL) for on-demand and in situ analysis has limited our ability to capitalize on this noninvasive and rich source of information. A wearable and miniaturized iontophoresis interface is an excellent solution to overcome this barrier. The iontophoresis process involves delivery of stimulating agonists to the sweat glands with the aid of an electrical current. The challenge remains in devising an iontophoresis interface that can extract sufficient amount of sweat for robust sensing,…

• NS
  National Science Foundation

  Award: DE-AC02-05CH11231
• UD
  U.S. Department of Energy

  Awards: -AC02-05CH11231, 05CH11231, Contract DE-AC02-05CH11231, AC02-05CH11231, DE-AC02, DE-AC02-05CH11231, DE-AC02-
• NI
  National Institutes of Health

  Awards: HG000205, P01 HG000205, DE-AC02-05CH11231
• OO
  Office of Science

  Awards: Contract DE-AC02-05CH11231, AC02-05CH11231, -AC02-05CH11231, DE-AC02
• BE
  Basic Energy Sciences

  Awards: DE-AC02, AC02-05CH11231, DE-AC02-05CH11231, -AC02-05CH11231, Contract DE-AC02-05CH11231