Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

Shakur‐Still, Haleema; Roberts, Ian; Fawole, Bukola; Chaudhri, Rizwana; El‐Sheikh, Mohamed A.; Akintan, Adesina; Qureshi, Zahida; Kidanto, Hussein; Vwalika, Bellington; Abdulkadir, Abdulfetah; Etuk, Saturday; Noor, Shehla; Asonganyi, Etienne; Alfirević, Žarko; Beaumont, Danielle; Ronsmans, Carine; Arulkumaran, Sabaratnam; Grant, Adrian; Afsana, Kaosar; Gülmezoglu, Metin; Hunt, Beverley J.; Olayemi, Oladapo; Roberts, Ian; Chalmers, Iain; Lumbiganon, Pisake; Piaggio, Gilda; Brady, Tony; Shakur‐Still, Haleema; Roberts, Ian; Alfirević, Žarko; Elbourne, Diana; Gülmezoglu, Metin; Ronsmans, Carine; Balogun, Eni; Pepple, Tracey; Prowse, Danielle; Quashi, Nigel; Barneston, Lin; Barrow, Collette; Beaumont, Danielle; Cook, Lisa; Frimley, Lauren; Gilbert, Daniel; Gilliam, Catherine; Jackson, Rob; Kawahara, Taemi; Miah, Hakim; Kostrov, Sergey; Ramos, Maria; Roberts, Ian; Shakur‐Still, Haleema; Edwards, Phil; Godec, Tom; Huque, Sumaya; Fawole, Bukola; Okunade, Olujide; Adetayo, Olusade; Chaudhri, Rizwana; Kayani, Aasia; Javaid, Kiran; Fawole, Bukola; Chaudhri, Rizwana; Biryabarema, Chrstine; Qureshi, Zahida; Tchounzou, Robert; El‐Sheikh, Mohamed A.; Kidanto, Hussein; Regmi, Mohan Chandra; Vwalika, Bellington; Dallaku, Kastriot; Sahani, Mateus; Akhter, Sayeba; Abdulkadir, Abdulfetah; Méda, Nicolas; Dah, Anthony Kwame; Akintan, Adesina; Odekunle, Olufemi; Monehin, Oluwabusola; Ojo, Austin; Akinbinu, Grace; Offiah, Ifeoma; Etuk, Saturday; Akpan, Ubong; Udofia, Uduak; Okon, Useneno; Omoronyia, Ezukwa; James, Okpe; Olayemi, Oladapo; Bello, Nike; Adeyemi, B F; Aimakhu, Chris; Akinsanya, Olufemi; Adeleye, Bamidele; Adeyemi, Oluwaseun; Oluwatosin, K. 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C.; Adeniyi, Augustine; Gbejegbe, Emmanuel Hero; Ikpen, Akpojaro; Nwosu, Ikemefuna; Sambo, Abdulrasaq; Ladipo, Olubunmi; Abubakar, Sola; Okike, Ola; Nduka, Enyinnaya Chikwendu; Ezenkwele, Eziamaka Pauline; Onwusulu, Daniel Nnaemeka; Irinyenikan, Theresa Azonima; Singh, Swati; Bariweni, Amaitari; Galadanci, Hadiza; Achara, Peter; Osayande, Osagie; Gana, Mohammed; Chaudhri, Rizwana; Jabeen, Kiran; Mobeen, Ayesha; Mufti, Sadaf; Zafar, Maliha; Noor, Shehla; Basharat, Ahmad; Munawar, Maimoona; Gul, Jeharat; Usman, Naseema; Shaheen, Fehmida; Tariq, Mariam; Sadiq, Nadia; Batool, Rabia; Ali, Habiba Sharaf; Jaffer, Manahil; Baloch, Asma; Mukhtiar, Noonari; Ashraf, Tasneem; Asmat, Raheela; Khudaidad, Salma; Taj, Ghazala; Qazi, Roshan Ara; Dars, Saira; Sardar, Faryal; Ashfaq, Sanobar; Majeed, Saeeda; Jabeen, Sadaqat; Karim, Rukhsana; Burki, Farzana; Bukhari, Syeda Rabia; Gul, Fouzia; Jabeen, Musarrat; Sherin, Akhtar; Ain, Qurratul; Rao, Shahid Irshad; Shaheen, Uzma; Manzoor, Samina; Masood, Shabween; Rizvi, Shabana; Ali, Anita; Sajid, Abida; Iftikhar, Aisha; Batool, Shazia; Dar, Lubna Riaz; Sohail, Shahenzad; Rasul, Shazia; Humayun, Shamsa; Sultana, Rashida; Manzoor, Sofia; Mazhar, Syeda Batool; Batool, Afshan; Nazir, Asia; Tasnim, Nasira; Masood, Hajira; Khero, Razia Bahadur; Surhio, Neelam; Aleem, Samana; Israr, Naila; Javed, Saba; Bashir, Lubna; Iqbal, Samina; Aleem, Faiza; Sohail, Rubina; Iqbal, Saima; Dojki, Samina Saleem; Bano, Alia; Saba, Naseem; Hafeez, Maimoona; Akram, Nishat; Israr, Naila; Shaheen, Riffat; Hashmi, Haleema A; Arshad, Sharmeen; Hussain, Rubina; Khan, Sadia Jabeen; Shaheen, Nighat; Khalil, Safia; Sachdev, Pushpa Sirichand; Arain, Gulfareen; Zarreen, Amtullah; Saeed, Sara; Hanif, Shamayela; Tariq, Nabia; Jamil, Mahwish; Chaudhry, Shama; Rajani, Hina; Wasim, Tayyiba; Aslam, Summera; Mustafa, Nilofar; Quddusi, Huma; Karim, Sajila; Sultana, Shazia; Harim, Misbah; Chohan, Mohd; Salman, Nabila; Waqar, Fareesa; Sadia, Shamsunnisa; Kahloon, Lubna; Manzoor, Shehla; Amin, Samar; Akram, Umbreen; Ikram, Ambreen; Kausar, Samina; Batool, Tahira; Naila, Brigadier; Kyani, Tahir; Biryabarema, Christine; Bulime, Ruth; Akello, Regina; Lwasa, Bernadette Nakawooya; Ayikoru, Joselyn; Namulwasira, Christine; Komagum, Patrick; Rebecca, I Schneider; Annet, Nayiga; Nuulu, Nakirigya; Nionzima, Elizabeth; Bwotya, Rose; Nankya, Margret; Babirye, Sarah; Ngonzi, Joseph; Cesar, Sanchez; Innocent, Nkonwa; Anitah, Kusasira; Jackson, Ayiko; Ndagire, Elizabeth; Nanyongo, Christine; Drametu, Dominic; Meregurwa, Grace; Banya, Francis; Atim, Rita; Byaruhanga, Emmanuel; Felix, Lema; Iman, Hussein; Oyiengo, Vincent; Waigi, Peninah; Wangui, Rose; Nassir, Faiza; Soita, Musimbi; Msengeti, Rophina; Zubier, Zeinab; Mabeya, Hillary; Wanjala, Antony; Mwangi, Henry; Liyayi, Brian; Muthoka, Evelyn; Osoti, Alfred; Otara, Amos; Ongwae, Veronicah; Qureshi, Zahida; Wanjohi, Victor; Musila, Bonface; Wekesa, Kubasu; Bosire, Alex Nyakundi; Asonganyi, Etienne; Ntem, Alice; Njoache, Angeline; Ashu, Alice; Simo, André; Tchounzou, Robert; Keka, Dorothy; Kenfack, Bruno; Ndouoya, Amadou; Saadio, Martin; Tchana, Mesack; Gwan, Odel; Assomo, Pauline; Mutsu, Venantius; Eric, Nji; Foumane, Pascal; Nsem, Philemon; Fouedjio, Jeanne Hortence; Fouelifack, Ymele; Tebeu, Pierre Marie; Nko'ayissi, Georges; Mbong, Eta Ngole; Nabag, Wisal Omer Mohamed; Desougi, Riham; Mustafa, Hadia; Eltaib, Huida; Umbeli, T; Elfadl, Khalid; Ibrahim, Murwan; Mohammed, Abdalla; Ali, Awadia; Abdelrahiem, Somia K.; Musa, Mohammed H.; Awadalla, Khidir E.; Ahmed, Samirra; Bushra, M.; Babiker, Omer; Abdullahi, Hala; Ahmed, Mohamed E.; Safa, Elhassan; Almardi, Huida; Rayis, Duria A.; Abdelgabar, Saeed Abdelrahman; Alfirević, Žarko; Houghton, Gillian; Sharpe, Andrew; Thornton, Jim; Grace, Nick; Smith, Carys; Hinshaw, Kim; Edmundson, Dawn; Ayuk, Paul; Bates, A.; Bugg, George; Wilkins, Joanne; Tower, Clare; Allibone, Alysha; Oteng-Ntim, Eugene; Kidanto, Hussein; Kazumari, Ahmad; Danford, A.; Ngarina, Matilda; Abeid, Muzdalifat; Mayumba, Khadija; 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doi:10.1016/s0140-6736(17)30638-4

articleThe LancetApr 26, 2017BRONZE OA

Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial

HSHaleema Shakur‐Still IRIan Roberts BFBukola Fawole RCRizwana Chaudhri MAMohamed A. El‐Sheikh

Pfizer (United Kingdom) · London School of Hygiene & Tropical Medicine · +1 more institution

PubMed

Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

1,424

total citations

FWCI: 60.53
Percentile: 100%
References: 24

Citations per year

Authors

493

HS
Haleema Shakur‐StillCorresponding
IR
Ian Roberts
BF
Bukola Fawole
Pfizer (United Kingdom), London School of Hygiene & Tropical Medicine, Wellcome Trust
RC
Rizwana Chaudhri
Pfizer (United Kingdom), London School of Hygiene & Tropical Medicine, Wellcome Trust
MA
Mohamed A. El‐Sheikh
Pfizer (United Kingdom), London School of Hygiene & Tropical Medicine, Wellcome Trust

Topics & keywords

Topics

Blood transfusion and management83%
Maternal and fetal healthcare3%
Cancer, Hypoxia, and Metabolism1%

Keywords

Tranexamic acid
Medicine
Post partum
Hysterectomy
Placebo
Double blind
Administration (probate law)
Obstetrics

UN Sustainable Development Goals

Good health and well-being

No related works found for this paper.

Funding

BA
Bill and Melinda Gates Foundation
Award: OPP1095618
P
Pfizer
W
Wellcome
Award: grant number WT094947
LS
London School of Hygiene and Tropical Medicine
WT
Wellcome Trust
Award: WT094947
DO
Department of Health and Social Care
Award: HICF-T2-0510-007