Psychiatric Genomics: An Update and an Agenda
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Abstract
The Psychiatric Genomics Consortium (PGC) is the largest consortium in the history of psychiatry. This global effort is dedicated to rapid progress and open science, and in the past decade it has delivered an increasing flow of new knowledge about the fundamental basis of common psychiatric disorders. The PGC has recently commenced a program of research designed to deliver "actionable" findings-genomic results that 1) reveal fundamental biology, 2) inform clinical practice, and 3) deliver new therapeutic targets. The central idea of the PGC is to convert the family history risk factor into biologically, clinically, and therapeutically meaningful insights. The emerging findings suggest that we are entering a…
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680
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- 68.63
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- 100%
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Authors
14Topics & keywords
Topics
Keywords
- Genomics
- MEDLINE
- Computational biology
- Psychiatry
- Psychology
- Medicine
- Biology
- Genetics
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Funding
- BIBroad Institute
- CVCohen Veterans Bioscience
- ECEuropean CommissionAwards: 667302, 602805
- SFScience Foundation Ireland
- LLundbeckfondenAward: U01 MH109528
- UIUniversitetet i Bergen
- HLH. Lundbeck A/S
- SCStanley Center for Psychiatric Research, Broad Institute
- MRMedical Research CouncilAwards: MR/P005748/1, MR/L010305/1
- NINational Institute of Mental HealthAwards: U01 MH085520, U01 MH109532, U01 MH094421, 5R01MH101519, U01 MH109536-01, U01 MH109528, MH109532, MH085520