articleeLifeDec 5, 2017GOLD OA

The Human Cell Atlas

ARAviv RegevSASarah A TeichmannESEric S LanderIAIdo AmitCBChristophe Benoist

Broad Institute · Howard Hughes Medical Institute · +60 more institutions

PubMed
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Abstract

The recent advent of methods for high-throughput single-cell molecular profiling has catalyzed a growing sense in the scientific community that the time is ripe to complete the 150-year-old effort to identify all cell types in the human body. The Human Cell Atlas Project is an international collaborative effort that aims to define all human cell types in terms of distinctive molecular profiles (such as gene expression profiles) and to connect this information with classical cellular descriptions (such as location and morphology). An open comprehensive reference map of the molecular state of cells in healthy human tissues would propel the systematic study of physiological states, developmental trajectories,…

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Authors

62
  • AR
    Aviv RegevCorresponding

    Broad Institute, Howard Hughes Medical Institute, Massachusetts Institute of Technology

  • SA
    Sarah A Teichmann

    European Bioinformatics Institute, University of Cambridge, Wellcome Sanger Institute

  • ES
    Eric S Lander

    Broad Institute, Harvard University, Center for Systems Biology, Massachusetts Institute of Technology

  • IA
    Ido Amit

    Weizmann Institute of Science

  • CB
    Christophe Benoist

    Harvard University

Topics & keywords

Topics
Keywords
  • Human cell
  • Atlas (anatomy)
  • Profiling (computer programming)
  • Human Protein Atlas
  • Gene expression profiling
  • Human genome
  • Cell
  • Human disease
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