Transition metal-catalyzed site- and regio-divergent C–H bond functionalization
Ewha Womans University · The Seoul Institute · +2 more institutions
Abstract
Recent advances in transition metal-catalyzed C-H bond functionalization have profoundly impacted synthetic strategy. Since organic substrates typically contain several chemically distinct C-H bonds, controlling the regioselectivity of C-H bond functionalization is imperative to harness its full potential. Moreover, the ability to alter reaction pathways to selectively functionalize different C-H bonds in a substrate represents a greater opportunity and challenge. The choice of catalysts, ligands, solvents, and even more subtle variations of the reaction conditions have been shown to allow the formation of regioisomeric C-H functionalization products starting from the same precursors. This review describes…
Citation impact
- FWCI
- 31.46
- Percentile
- 100%
- References
- 347
Authors
4- LPLucy Ping
Ewha Womans University, The Seoul Institute, Ewha Womans University Medical Center, PLUS Foundation
- DSDa Sol Chung
Ewha Womans University, The Seoul Institute, Ewha Womans University Medical Center, PLUS Foundation
- JBJean BouffardCorresponding
Ewha Womans University, The Seoul Institute, Ewha Womans University Medical Center, PLUS Foundation
- SLSang‐gi LeeCorresponding
Ewha Womans University, The Seoul Institute, Ewha Womans University Medical Center, PLUS Foundation
Topics & keywords
- Surface modification
- Regioselectivity
- Catalysis
- Chemistry
- Transition metal
- Combinatorial chemistry
- Organic synthesis
- Substrate (aquarium)