SERS-Activated Platforms for Immunoassay: Probes, Encoding Methods, and Applications

Wang, Zhuyuan; Zong, Shenfei; Wu, Lei; Zhu, Dan; Cui, Yiping

doi:10.1021/acs.chemrev.7b00027

reviewChemical ReviewsMay 23, 2017Closed access

SERS-Activated Platforms for Immunoassay: Probes, Encoding Methods, and Applications

ZWZhuyuan Wang SZShenfei Zong LWLei Wu DZDan Zhu YCYiping Cui

Southeast University

PubMed

Indexed incrossrefpubmed

Abstract

Owing to their excellent multiplexing ability, high sensitivity, and large dynamic range, immunoassays using surface-enhanced Raman scattering (SERS) as the readout signal have found prosperous applications in fields such as disease diagnosis, environmental surveillance, and food safety supervision. Various ever-increasing demands have promoted SERS-based immunoassays from the classical sandwich-type ones to those integrated with fascinating automatic platforms (e.g., test strips and microfluidic chips). As recent years have witnessed impressive progress in SERS immunoassays, we try to comprehensively cover SERS-based immunoassays from their basic working principles to specific applications. Focusing on…

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Topics

Keywords

Immunoassay
Nanotechnology
Multiplexing
Computer science
Microfluidics
Telecommunications
Materials science

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