Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine
Hallym University · Galgotias University · +2 more institutions
Abstract
In the past few years, therapeutic microRNA (miRNA) and small interfering RNA (siRNA) are some of the most important biopharmaceuticals that are in commercial space as future medicines. This review summarizes the patents of miRNA- and siRNA-based new drugs, and also provides a snapshot about significant biopharmaceutical companies that are investing for the therapeutic development of miRNA and siRNA molecules. An insightful view about individual siRNA and miRNA drugs has been depicted with their present status, which is gaining attention in the therapeutic landscape. The efforts of the biopharmaceuticals are discussed with the status of their preclinical and/or clinical trials. Here, some of the setbacks have…
Citation impact
- FWCI
- 44.85
- Percentile
- 100%
- References
- 90
Authors
5- CCChiranjib ChakrabortyCorresponding
Hallym University, Galgotias University, Hallym University Chuncheon Sacred Heart Hospital
- ARAshish Ranjan Sharma
Hallym University, Hallym University Chuncheon Sacred Heart Hospital
- GSGarima Sharma
Hallym University, Hallym University Chuncheon Sacred Heart Hospital
- CGC. George Priya Doss
Vellore Institute of Technology University
- SLSang‐Soo LeeCorresponding
Hallym University, Hallym University Chuncheon Sacred Heart Hospital
Topics & keywords
- Biopharmaceutical
- microRNA
- Small interfering RNA
- Gene silencing
- Computational biology
- Bench to bedside
- ADME
- Medicine