Emerging Nanotechnology and Advanced Materials for Cancer Radiation Therapy
Soochow University · Stanford Medicine · +1 more institution
Abstract
Radiation therapy (RT) including external beam radiotherapy (EBRT) and internal radioisotope therapy (RIT) has been widely used for clinical cancer treatment. However, owing to the low radiation absorption of tumors, high doses of ionizing radiations are often needed during RT, leading to severe damages to normal tissues adjacent to tumors. Meanwhile, the RT efficacies are limited by different mechanisms, among which the tumor hypoxia-associated radiation resistance is a well-known one, as there exists hypoxia inside most solid tumors while oxygen is essential to enhance radiation-induced DNA damages. With the development in nanotechnology, there have been great interests in using nanomedicine strategies to…
Citation impact
- FWCI
- 26.50
- Percentile
- 100%
- References
- 272
Authors
5Topics & keywords
- Nanomedicine
- Radiation therapy
- Cancer research
- Tumor hypoxia
- Ionizing radiation
- Cancer treatment
- Cancer
- Materials science