Recent progress in surface-enhanced Raman spectroscopy for biological and biomedical applications: from cells to clinics
Helmholtz Institute Jena · Leibniz Institute of Photonic Technology · +3 more institutions
Abstract
The application of surface-enhanced Raman spectroscopy (SERS) in biological and biomedical detection schemes is feasible due to its excellent molecular specificity and high sensitivity as well as the capability of SERS to be performed in complex biological compositions. SERS-based investigation of cells, which are the basic structure and functional unit of organisms, represents the starting point of this review. It is demonstrated that SERS provides a deep understanding of living cells as well as their microenvironment which is needed to assess the development of diseases. The clinical relevance of SERS is proved by its application for the detection of cancer cells and tumour margins under in vivo conditions…
Citation impact
- FWCI
- 21.91
- Percentile
- 100%
- References
- 50
Authors
4- DCDana Cialla‐May
Helmholtz Institute Jena, Leibniz Institute of Photonic Technology, EM Photonics (United States), InfectoGnostics Research Campus Jena, Friedrich Schiller University Jena
- XZXiaoshan Zheng
Leibniz Institute of Photonic Technology
- KWKarina Weber
Helmholtz Institute Jena, Leibniz Institute of Photonic Technology, EM Photonics (United States), InfectoGnostics Research Campus Jena, Friedrich Schiller University Jena
- JPJürgen PoppCorresponding
Helmholtz Institute Jena, Leibniz Institute of Photonic Technology, EM Photonics (United States), InfectoGnostics Research Campus Jena, Friedrich Schiller University Jena
Topics & keywords
- Nanotechnology
- Surface-enhanced Raman spectroscopy
- Raman spectroscopy
- Materials science
- Computer science
- Physics
- Raman scattering
- Optics