reviewChemical ReviewsJun 22, 2017Closed access

Recent Advances in Radical C–H Activation/Radical Cross-Coupling

Wuhan University · Jiangxi Normal University

PubMed
Indexed incrossrefpubmed

Abstract

Research and industrial interest in radical C-H activation/radical cross-coupling chemistry has continuously grown over the past few decades. These reactions offer fascinating and unconventional approaches toward connecting molecular fragments with high atom- and step-economy that are often complementary to traditional methods. Success in this area of research was made possible through the development of photocatalysis and first-row transition metal catalysis along with the use of peroxides as radical initiators. This Review provides a brief and concise overview of the current status and latest methodologies using radicals or radical cations as key intermediates produced via radical C-H activation. This Review…

Citation impact

1,291
total citations
FWCI
67.12
Percentile
100%
References
320
Citations per year

Authors

7

Topics & keywords

Keywords
  • Chemistry
  • Radical
  • Nucleophile
  • Radical ion
  • Radical cyclization
  • Radical substitution
  • Radical disproportionation
  • Atom economy
UN Sustainable Development Goals
  • Industry, innovation and infrastructure
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