articleAngewandte Chemie International EditionJun 22, 2017Closed access

Antimonene Quantum Dots: Synthesis and Application as Near‐Infrared Photothermal Agents for Effective Cancer Therapy

WTWei TaoXJXiaoyuan JiXXXiaoding XuMAMohammad Ariful IslamZLZhongjun Li

Brigham and Women's Hospital · Harvard University · +3 more institutions

PubMed
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Abstract

Abstract Photothermal therapy (PTT) has shown significant potential for cancer therapy. However, developing nanomaterials (NMs)‐based photothermal agents (PTAs) with satisfactory photothermal conversion efficacy (PTCE) and biocompatibility remains a key challenge. Herein, a new generation of PTAs based on two‐dimensional (2D) antimonene quantum dots (AMQDs) was developed by a novel liquid exfoliation method. Surface modification of AMQDs with polyethylene glycol (PEG) significantly enhanced both biocompatibility and stability in physiological medium. The PEG‐coated AMQDs showed a PTCE of 45.5 %, which is higher than many other NMs‐based PTAs such as graphene, Au, MoS 2 , and black phosphorus (BP). The…

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528
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12

Topics & keywords

Topics
Keywords
  • Photothermal therapy
  • Biocompatibility
  • Nanomaterials
  • Polyethylene glycol
  • Nanotechnology
  • Exfoliation joint
  • Cancer therapy
  • Materials science
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