The molecular mechanisms of chemoresistance in cancers
Indexed incrossrefpubmed
Abstract
// Hua-Chuan Zheng 1 1 Department of Experimental Oncology and Animal Center, Shengjing Hospital of China Medical University, Shenyang 110004, China Correspondence to: Hua-Chuan Zheng, email: zheng_huachuan@hotmail.com Keywords: cancer, chemoresistance, molecular mechanisms, chemotherapy Received: March 31, 2017 Accepted: June 24, 2017 Published: July 06, 2017 ABSTRACT Overcoming intrinsic and acquired drug resistance is a major challenge in treating cancer patients because chemoresistance causes recurrence, cancer dissemination and death. This review summarizes numerous molecular aspects of multi-resistance, including transporter pumps, oncogenes…
Citation impact
600
total citations
- FWCI
- 26.28
- Percentile
- 100%
- References
- 128
Citations per year
Authors
1Topics & keywords
Topics
Keywords
- Protein kinase B
- Survivin
- Cancer research
- PI3K/AKT/mTOR pathway
- Medicine
- Epithelial–mesenchymal transition
- Cancer
- Autophagy
UN Sustainable Development Goals
- Good health and well-being
No related works found for this paper.