reviewMass Spectrometry ReviewsJul 9, 2017Closed access

The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics

LKLindsay K. PinoBCBrian C. SearleJGJames G. BollingerBLBrook L. NunnBMBrendan MacLean

University of Washington

PubMed
Indexed incrossrefpubmed

Abstract

Skyline is a freely available, open-source Windows client application for accelerating targeted proteomics experimentation, with an emphasis on the proteomics and mass spectrometry community as users and as contributors. This review covers the informatics encompassed by the Skyline ecosystem, from computationally assisted targeted mass spectrometry method development, to raw acquisition file data processing, and quantitative analysis and results sharing.

Citation impact

881
total citations
FWCI
17.81
Percentile
100%
References
98
Citations per year

Authors

6

Topics & keywords

Topics
Keywords
  • Skyline
  • Proteomics
  • Chemistry
  • Mass spectrometry
  • Health informatics tools
  • Quantitative proteomics
  • Informatics
  • Data science
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