Ultralong Phosphorescence of Water‐Soluble Organic Nanoparticles for In Vivo Afterglow Imaging
Nanyang Technological University · Nanjing University of Posts and Telecommunications · +2 more institutions
Abstract
Afterglow or persistent luminescence eliminates the need for light excitation and thus circumvents the issue of autofluorescence, holding promise for molecular imaging. However, current persistent luminescence agents are rare and limited to inorganic nanoparticles. This study reports the design principle, synthesis, and proof-of-concept application of organic semiconducting nanoparticles (OSNs) with ultralong phosphorescence for in vivo afterglow imaging. The design principle leverages the formation of aggregates through a top-down nanoparticle formulation to greatly stabilize the triplet excited states of a phosphorescent molecule. This prolongs the particle luminesce to the timescale that can be detected by…
Citation impact
- FWCI
- 19.29
- Percentile
- 100%
- References
- 46
Authors
8Topics & keywords
- Phosphorescence
- Afterglow
- Persistent luminescence
- Luminescence
- Materials science
- Nanoparticle
- Nanotechnology
- Photochemistry
- Clean water and sanitation
Funding
- NUNorthwestern University
- MOMinistry of Education - Singapore
- NTNanyang Technological UniversityAwards: M4081627.120, Tier 1, NTU‐SUG: M4081627.120, M4081627, NTU-SUG: M4081627.120, NTU-SUG: M4081627
- NNNational Natural Science Foundation of ChinaAwards: 21674049, 2015CB932200, 61136003, 21304049
- MOMinistry of Education, India