articleNature GeneticsOct 30, 2017GREEN OA

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

RMRobin M. MeyersJBJordan BryanJMJames M. McFarlandBABarbara A. WeirAEAnn E. Sizemore

Broad Institute · Boston Children's Hospital · +4 more institutions

PubMed
Indexed incrossrefpubmed

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Topics & keywords

Topics
Keywords
  • CRISPR
  • Biology
  • Cas9
  • Computational biology
  • Gene
  • Genetics
  • Genome
  • Genome editing
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