Mapping of human brown adipose tissue in lean and obese young men
National Institutes of Health · National Institute of Diabetes and Digestive and Kidney Diseases · +5 more institutions
Abstract
F-labeled fluorodeoxyglucose positron emission tomography/computerized tomography (PET/CT). Obese men had less activated BAT than lean men (mean, 130 vs. 334 mL) but more fat in BAT-containing depots (mean, 1,646 vs. 855 mL) with a wide range (0.1-71%) in the ratio of activated BAT to inactive fat between individuals. Six anatomic regions had activated BAT-cervical, supraclavicular, axillary, mediastinal, paraspinal, and abdominal-with 67 ± 20% of all activated BAT concentrated in a continuous fascial layer comprising the first three depots in the upper torso. These nonsubcutaneous fat depots amounted to 1.5% of total body mass (4.3% of total fat mass), and up to 90% of each depot could be activated BAT. The…
Citation impact
- FWCI
- 27.54
- Percentile
- 100%
- References
- 44
Authors
14- BPBrooks P. LeitnerCorresponding
National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
- SHShan Huang
National Institutes of Health, Fudan University, National Institute of Diabetes and Digestive and Kidney Diseases, Huashan Hospital
- RJRobert J. Brychta
National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
- CJCourtney J. Duckworth
National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
- ASAlison S. Baskin
National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
Topics & keywords
- Adipose tissue
- Obesity
- Human obesity
- Brown adipose tissue
- Medicine
- Internal medicine
- Good health and well-being