A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
University of Pennsylvania · Novartis (United States) · +4 more institutions
Indexed incrossref
Abstract
A trial of autologous T cells redirected to a specific mutation in glioblastoma patients illustrates mechanisms of resistance.
Citation impact
1,760
total citations
- FWCI
- 58.30
- Percentile
- 100%
- References
- 51
Citations per year
Authors
21Topics & keywords
Topics
Keywords
- Glioblastoma
- Antigen
- Cancer research
- Medicine
- Mutation
- Immunology
- Biology
- Gene
No related works found for this paper.