review·Cell Metabolism·Aug 1, 2017BRONZE OA

The Dawn of the Age of Amino Acid Sensors for the mTORC1 Pathway

RLRachel L. WolfsonCorresponding authorDMDavid M. Sabatini

Broad Institute · Howard Hughes Medical Institute · +3 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

554
total citations
FWCI
26.69
Percentile
100%
References
62
Citations per year

Authors

2
  • RL
    Rachel L. WolfsonCorresponding

    Broad Institute, Howard Hughes Medical Institute, Whitehead Institute for Biomedical Research, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology

  • DM
    David M. Sabatini

    Broad Institute, Howard Hughes Medical Institute, Whitehead Institute for Biomedical Research, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology

Topics & keywords

Topics
  • Primary topicPI3K/AKT/mTOR signaling in cancer100%
  • Polyamine Metabolism and Applications100%
  • Protein Kinase Regulation and GTPase Signaling100%
Keywords
  • mTORC1
  • Amino acid
  • Regulator
  • Computational biology
  • Biology
  • Identification (biology)
  • Master regulator
  • Signal transduction
No related works found for this paper.

Funding

  • UD
    U.S. Department of Defense
    Award: W81XWH-15-1-0230
  • NI
    National Institutes of Health
    Awards: T32 GM007753, R01 CA103866, F30 CA189333, AI47389