articleNew England Journal of MedicineAug 23, 2017BRONZE OA

Global, Regional, and National Burden of Rheumatic Heart Disease, 1990–2015

Institute for Health Metrics and Evaluation · Groote Schuur Hospital · +16 more institutions

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Abstract

Background

Rheumatic heart disease remains an important preventable cause of cardiovascular death and disability, particularly in low-income and middle-income countries. We estimated global, regional, and national trends in the prevalence of and mortality due to rheumatic heart disease as part of the 2015 Global Burden of Disease study.

Methods

We systematically reviewed data on fatal and nonfatal rheumatic heart disease for the period from 1990 through 2015. Two Global Burden of Disease analytic tools, the Cause of Death Ensemble model and DisMod-MR 2.1, were used to produce estimates of mortality and prevalence, including estimates of uncertainty.

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