Recent Advances in the Chemical Synthesis of C -Glycosides
East China University of Science and Technology · Chinese Academy of Sciences · +1 more institution
Abstract
Advances in the chemical synthesis of C-pyranosides/furanosides are summarized, covering the literature from 2000 to 2016. The majority of the methods take advantage of the construction of the glycosidic C-C bond. These C-glycosylation methods are categorized herein in terms of the glycosyl donor precursors, which are commonly used in O-glycoside synthesis and are easily accessible to nonspecialists. They include glycosyl halides, glycals, sugar acetates, sugar lactols, sugar lactones, 1,2-anhydro sugars, thioglycosides/sulfoxides/sulfones, selenoglycosides/telluroglycosides, methyl glycosides, and glycosyl imidates/phosphates. Mechanistically, C-glycosylation reactions can involve glycosyl…
Citation impact
- FWCI
- 19.13
- Percentile
- 100%
- References
- 768
Authors
2Topics & keywords
- Chemistry
- Glycosidic bond
- Glycosyl
- Glycosylation
- Glycal
- Intramolecular force
- Stereochemistry
- Electrophile
Funding
- NNNational Natural Science Foundation of ChinaAwards: 21432012, 21621002
- CAChinese Academy of SciencesAward: XDB20020000
- MOMinistry of Science and Technology of the People's Republic of ChinaAward: 2012ZX09502-002
- SAScience and Technology Commission of Shanghai MunicipalityAward: 15PJ1401500
- SMShanghai Municipal Human Resources and Social Security BureauAward: 15PJ1401500
- KCK. C. Wong Education Foundation