Hippocampal GABAergic Inhibitory Interneurons
Centre National de la Recherche Scientifique · National Institutes of Health · +7 more institutions
Abstract
In the hippocampus GABAergic local circuit inhibitory interneurons represent only ~10-15% of the total neuronal population; however, their remarkable anatomical and physiological diversity allows them to regulate virtually all aspects of cellular and circuit function. Here we provide an overview of the current state of the field of interneuron research, focusing largely on the hippocampus. We discuss recent advances related to the various cell types, including their development and maturation, expression of subtype-specific voltage- and ligand-gated channels, and their roles in network oscillations. We also discuss recent technological advances and approaches that have permitted high-resolution,…
Citation impact
- FWCI
- 28.20
- Percentile
- 100%
- References
- 1,301
Authors
6- KAKenneth A. PelkeyCorresponding
Centre National de la Recherche Scientifique, National Institutes of Health, Inserm, Université Paris Cité, University of Exeter, Sorbonne Université, Institut de Biologie Paris-Seine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Neurosciences Paris-Seine
- RCRamesh Chittajallu
Centre National de la Recherche Scientifique, National Institutes of Health, Inserm, Université Paris Cité, University of Exeter, Sorbonne Université, Institut de Biologie Paris-Seine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Neurosciences Paris-Seine
- MTMichael T. Craig
Centre National de la Recherche Scientifique, National Institutes of Health, Inserm, Université Paris Cité, University of Exeter, Sorbonne Université, Institut de Biologie Paris-Seine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Neurosciences Paris-Seine
- LTLudovic Tricoire
Centre National de la Recherche Scientifique, National Institutes of Health, Inserm, Université Paris Cité, University of Exeter, Sorbonne Université, Institut de Biologie Paris-Seine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Neurosciences Paris-Seine
- JCJason C. Wester
Centre National de la Recherche Scientifique, National Institutes of Health, Inserm, Université Paris Cité, University of Exeter, Sorbonne Université, Institut de Biologie Paris-Seine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Neurosciences Paris-Seine
Topics & keywords
- Neuroscience
- GABAergic
- Interneuron
- Hippocampal formation
- Inhibitory postsynaptic potential
- Biology
- Hippocampus
- Population