Muscle fatigue: general understanding and treatment

Muscle fatigue is a common complaint in clinical practice. In humans, muscle fatigue can be defined as exercise-induced decrease in the ability to produce force. Here, to provide a general understanding and describe potential therapies for muscle fatigue, we summarize studies on muscle fatigue, including topics such as the sequence of events observed during force production, in vivo fatigue-site evaluation techniques, diagnostic markers and non-specific but effective treatments. Muscle fatigue after exercise is only partially understood and more research is needed to uncover its mechanisms and develop treatments. Xia Liu, Yang Sun and colleagues at the Second Military Medical University in Shanghai, reviewed…

• NN
  National Natural Science Foundation of China

  Awards: 81473259, 81273606
• NS
  National Science and Technology Major Project