A Two-Dimensional Biodegradable Niobium Carbide (MXene) for Photothermal Tumor Eradication in NIR-I and NIR-II Biowindows
Chinese Academy of Sciences · Shanghai Institute of Ceramics · +1 more institution
Abstract
Conventionally, ceramics-based materials, fabricated by high-temperature solid-phase reaction and sintering, are preferred as bone scaffolds in hard-tissue engineering because of their tunable biocompatibility and mechanical properties. However, their possible biomedical applications have rarely been considered, especially the cancer phototherapeutic applications in both the first and second near-infrared light (NIR-I and NIR-II) biowindows. In this work, we explore, for the first time as far as we know, a novel kind of 2D niobium carbide (Nb2C), MXene, with highly efficient in vivo photothermal ablation of mouse tumor xenografts in both NIR-I and NIR-II windows. The 2D Nb2C nanosheets (NSs) were fabricated by…
Citation impact
- FWCI
- 41.01
- Percentile
- 100%
- References
- 57
Authors
5- HLHan LinCorresponding
Chinese Academy of Sciences, Shanghai Institute of Ceramics, University of Chinese Academy of Sciences
- SGShanshan Gao
Chinese Academy of Sciences, Shanghai Institute of Ceramics, University of Chinese Academy of Sciences
- CDChen Dai
Chinese Academy of Sciences, Shanghai Institute of Ceramics
- YCYu Chen
Chinese Academy of Sciences, Shanghai Institute of Ceramics
- JSJianlin Shi
Chinese Academy of Sciences, Shanghai Institute of Ceramics
Topics & keywords
- Photothermal therapy
- MXenes
- Biocompatibility
- Nanotechnology
- Chemistry
- Materials science
- Organic chemistry
Funding
- CAChina Association for Science and TechnologyAward: 2015QNRC001
- NNNational Natural Science Foundation of ChinaAwards: 51672303, 51722211
- MOMinistry of Science and Technology of the People's Republic of ChinaAward: 2016YFA0203700
- YIYouth Innovation Promotion Association of the Chinese Academy of SciencesAward: 2013169