reviewPLoS ONEOct 17, 2017GOLD OA

Advanced maternal age and adverse pregnancy outcomes: A systematic review and meta-analysis

Manchester Academic Health Science Centre · University of Manchester · +2 more institutions

PubMed
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Abstract

Background

Advanced maternal age (AMA; ≥35 years) is an increasing trend and is reported to be associated with various pregnancy complications.

Objective

To determine the risk of stillbirth and other adverse pregnancy outcomes in women of AMA. SEARCH STRATEGY: Embase, Medline (Ovid), Cochrane Database of Systematic Reviews, ClinicalTrials.gov, LILACS and conference proceedings were searched from ≥2000. SELECTION CRITERIA: Cohort and case-control studies reporting data on one or more co-primary outcomes (stillbirth or fetal growth restriction (FGR)) and/or secondary outcomes in mothers ≥35 years and

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