articleJournal of Biomaterials Science Polymer EditionOct 20, 2017Closed access

PCL and PCL-based materials in biomedical applications

EMElbay MalikmammadovTETuğba Endoğan TanırAKAysel KızıltayVHVasıf HasırcıNHNesrin Hasırcı

Middle East Technical University

PubMed
Indexed incrossrefpubmed

Abstract

Biodegradable polymers have met with an increasing demand in medical usage over the last decades. One of such polymers is poly(ε-caprolactone) (PCL), which is a polyester that has been widely used in tissue engineering field for its availability, relatively inexpensive price and suitability for modification. Its chemical and biological properties, physicochemical state, degradability and mechanical strength can be adjusted, and therefore, it can be used under harsh mechanical, physical and chemical conditions without significant loss of its properties. Degradation time of PCL is quite long, thus it is used mainly in the replacement of hard tissues in the body where healing also takes an extended period of…

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860
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Authors

5

Topics & keywords

Topics
Keywords
  • Materials science
  • Polyester
  • Polymer
  • Tissue engineering
  • Drug delivery
  • Degradation (telecommunications)
  • Mechanical strength
  • Composite material
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