articleCell chemical biologyNov 9, 2017BRONZE OA

The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

GMGeorge M. BurslemBEBlake E. SmithACAshton C. LaiSJSaul Jaime‐FigueroaDMDaniel McQuaid

Yale University · Arvinas (United States)

PubMed
Indexed incrossrefpubmed

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Topics & keywords

Topics
Keywords
  • Kinome
  • Protein degradation
  • Receptor tyrosine kinase
  • Ubiquitin ligase
  • Tyrosine kinase
  • Proteolysis
  • Ubiquitin
  • Target protein
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