Towards a genomics-informed, real-time, global pathogen surveillance system
University of British Columbia · BC Centre for Disease Control · +1 more institution
Abstract
Next-generation sequencing has the potential to support public health surveillance systems to improve the early detection of emerging infectious diseases. This Review delineates the role of genomics in rapid outbreak response and the challenges that need to be tackled for genomics-informed pathogen surveillance to become a global reality. The recent Ebola and Zika epidemics demonstrate the need for the continuous surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast, affordable sequencing of pathogen genomes — now a staple of the public health microbiology laboratory in well-resourced settings — can affect each of these areas. Coupling genomic diagnostics and epidemiology…
Citation impact
- FWCI
- 62.53
- Percentile
- 100%
- References
- 122
Authors
2Topics & keywords
- Genomics
- Infectious disease (medical specialty)
- Public health
- Biology
- Data science
- Disease surveillance
- Public health surveillance
- Citizen science
- Good health and well-being