Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery
University of Toronto · St Michael's Hospital · +32 more institutions
Abstract
The effect of a restrictive versus liberal red-cell transfusion strategy on clinical outcomes in patients undergoing cardiac surgery remains unclear.
In this multicenter, open-label, noninferiority trial, we randomly assigned 5243 adults undergoing cardiac surgery who had a European System for Cardiac Operative Risk Evaluation (EuroSCORE) I of 6 or more (on a scale from 0 to 47, with higher scores indicating a higher risk of death after cardiac surgery) to a restrictive red-cell transfusion threshold (transfuse if hemoglobin level was
Citation impact
- FWCI
- 33.43
- Percentile
- 100%
- References
- 37
Authors
31- CDC. David MazerCorresponding
University of Toronto, St Michael's Hospital
- RWRichard Whitlock
Health Sciences Centre, Population Health Research Institute, McMaster University, Hamilton Health Sciences, St Michael's Hospital
- DFDean Fergusson
St Michael's Hospital, University of Ottawa, Ottawa Hospital
- JEJudith E. Hall
University of Toronto, St Michael's Hospital, St. Michael's Hospital
- EPEmilie P. Belley‐Côté
Population Health Research Institute, St Michael's Hospital, McMaster University, Hamilton Health Sciences, Health Sciences Centre
Topics & keywords
- Medicine
- Odds ratio
- Confidence interval
- Cardiac surgery
- Intensive care unit
- Myocardial infarction
- Dialysis
- Stroke (engine)