Exosome Theranostics: Biology and Translational Medicine

Exosomes are common membrane-bound nanovesicles that contain diverse biomolecules, such as lipids, proteins, and nucleic acids. Exosomes are derived from cells through exocytosis, are ingested by target cells, and can transfer biological signals between local or distant cells. Exosome secretion is a constitutive phenomenon that is involved in both physiological and pathological processes and determines both the exosomal surface molecules and the contents. Hence, we can exploit exosomes as biomarkers, vaccines and drug carriers and modify them rationally for therapeutic interventions. However, it is still a challenge to identify, isolate and quantify exosomes accurately, efficiently and selectively. Further…

• NS
  National Science Foundation
• NN
  National Natural Science Foundation of China

  Awards: 81570168, 81401541
• SA
  Science and Technology Department of Zhejiang Province
• NS
  Natural Science Foundation of Zhejiang Province

  Award: LR16H180001