reviewJournal of Natural MedicinesNov 21, 2017HYBRID OA

Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites

SSSeiichi SakamotoWPWaraporn PutalunSVSornkanok VimolmangkangWPWaranyoo PhoolcharoenYSYukihiro Shoyama

Kyushu University · Khon Kaen University · +2 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Immunoassays are antibody-based analytical methods for quantitative/qualitative analysis. Since the principle of immunoassays is based on specific antigen-antibody reaction, the assays have been utilized worldwide for diagnosis, pharmacokinetic studies by drug monitoring, and the quality control of commercially available products. Berson and Yalow were the first to develop an immunoassay, known as radioimmunoassay (RIA), for detecting endogenous plasma insulin [1], a development for which Yalow was awarded the Nobel Prize in Physiology or Medicine in 1977. Even today, after half a century, immunoassays are widely utilized with some modifications from the originally proposed system, e.g., radioisotopes have…

Citation impact

594
total citations
FWCI
9.42
Percentile
100%
References
72
Citations per year

Authors

7

Topics & keywords

Topics
Keywords
  • Immunoassay
  • Radioimmunoassay
  • Antibody
  • Enzyme
  • Recombinant DNA
  • Chemistry
  • Chromatography
  • Pharmacology
UN Sustainable Development Goals
  • Good health and well-being
No related works found for this paper.

Funding