Ten simple rules for neuroimaging meta-analysis

Neuroimaging has evolved into a widely used method to investigate the functional neuroanatomy, brain-behaviour relationships, and pathophysiology of brain disorders, yielding a literature of more than 30,000 papers. With such an explosion of data, it is increasingly difficult to sift through the literature and distinguish spurious from replicable findings. Furthermore, due to the large number of studies, it is challenging to keep track of the wealth of findings. A variety of meta-analytical methods (coordinate-based and image-based) have been developed to help summarise and integrate the vast amount of data arising from neuroimaging studies. However, the field lacks specific guidelines for the conduct of such…

• W
  Wellcome

  Award: 100309/Z/12/Z
• WT
  Wellcome Trust

  Award: 100309/Z/12/Z
• EC
  European Commission

  Award: HBP SGA1
• DF
  Deutsche Forschungsgemeinschaft

  Awards: 816/4-1, 3071/3-1, EI 816/4-1, LA 3071/3-1
• NI
  National Institutes of Health

  Awards: 2R01MH076136, MH074457, 100309/Z/12/Z, R01DA035484, R01-MH074457
• NI
  National Institute of Mental Health

  Awards: R01-MH074457, MH074457