articleNatureNov 16, 2017GREEN OA

Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

Harvard University · Beth Israel Deaconess Medical Center · +10 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

No abstract available for this paper.

Citation impact

1,028
total citations
FWCI
50.46
Percentile
100%
References
43
Citations per year

Authors

18

Topics & keywords

Keywords
  • Cullin
  • Cancer research
  • Ubiquitin ligase
  • PD-L1
  • Immune checkpoint
  • Cyclin-dependent kinase 6
  • Durvalumab
  • Protein degradation
UN Sustainable Development Goals
  • Good health and well-being
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