articleNucleic Acids ResearchOct 27, 2017GOLD OA

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework

AKAziz KhanOFOriol FornésASArnaud StiglianiMGMarius GheorgheJAJaime A. Castro-Mondragón

University of Oslo · University of British Columbia · +16 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

JASPAR (http://jaspar.genereg.net) is an open-access database of curated, non-redundant transcription factor (TF)-binding profiles stored as position frequency matrices (PFMs) and TF flexible models (TFFMs) for TFs across multiple species in six taxonomic groups. In the 2018 release of JASPAR, the CORE collection has been expanded with 322 new PFMs (60 for vertebrates and 262 for plants) and 33 PFMs were updated (24 for vertebrates, 8 for plants and 1 for insects). These new profiles represent a 30% expansion compared to the 2016 release. In addition, we have introduced 316 TFFMs (95 for vertebrates, 218 for plants and 3 for insects). This release incorporates clusters of similar PFMs in each taxon and each TF…

Citation impact

1,602
total citations
FWCI
93.63
Percentile
100%
References
50
Citations per year

Authors

19

Topics & keywords

Topics
Keywords
  • Biology
  • Bioconductor
  • Genome
  • Genome browser
  • Database
  • Transcription factor
  • Computational biology
  • Computer science
No related works found for this paper.

Funding