articleAdvanced MaterialsDec 11, 2017Closed access

Theranostic 2D Tantalum Carbide (MXene)

Chinese Academy of Sciences · Shanghai Institute of Ceramics · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Abstract The large‐dimensional and rigid ceramic bulks fabricated by high‐temperature solid‐phase reaction and sintering have never been considered for possibly entering and circulating within the blood vessels for biomedical applications, especially on combating cancer. Here, it is reported for the first time that MAX ceramic biomaterials exhibit unique functionalities for dual‐mode photoacoustic/computed tomography imaging and are highly effective for in vivo photothermal ablation of tumors upon being exfoliated into ultrathin nanosheets within atomic thickness (MXene). As a paradigm, 2D ultrathin tantalum carbide nanosheets (Ta 4 C 3 MXenes) with nanosized lateral sizes are successfully synthesized based on…

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