Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software

The Critical Assessment of Metagenome Interpretation (CAMI) community initiative presents results from its first challenge, a rigorous benchmarking of software for metagenome assembly, binning and taxonomic profiling. Methods for assembly, taxonomic profiling and binning are key to interpreting metagenome data, but a lack of consensus about benchmarking complicates performance assessment. The Critical Assessment of Metagenome Interpretation (CAMI) challenge has engaged the global developer community to benchmark their programs on highly complex and realistic data sets, generated from ∼700 newly sequenced microorganisms and ∼600 novel viruses and plasmids and representing common experimental setups. Assembly…

• NS
  National Science Foundation

  Awards: 1041726, EP/K032208/1, OCI-1053575, 1053575, DE-AC02-05CH11231, 1445606, 1458689, ACI-1445606
• UD
  U.S. Department of Energy

  Awards: -AC02-05CH11231, 05CH11231, OCI-1053575, AC02-05CH11231, DE-AC02, DE-AC02-05CH11231, DE-AC02-
• VF
  Villum Fonden

  Award: R44-A4384
• IN
  Isaac Newton Institute for Mathematical Sciences

  Award: EP/K032208/1
• JG
  Joint Genome Institute

  Awards: DE-AC02-05CH11231, AC02-05CH11231
• AF
  Agency for Science, Technology and Research
• DF
  Deutsche Forschungsgemeinschaft

  Award: DE-AC02-05CH11231
• L
  Lundbeckfonden

  Award: R44-A4384
• HL
  H. Lundbeck A/S
• OO
  Office of Science

  Awards: AC02-05CH11231, -AC02-05CH11231, DE-AC02
• MR
  Medical Research Council

  Awards: MR/M50161X/1, MR/L015080/1
• EA
  Engineering and Physical Sciences Research Council

  Awards: DE-AC02-05CH11231, EP/K032208/1, EP/K032208, EP/K032208/1
• BA
  Biotechnology and Biological Sciences Research Council

  Award: BB/L027801/1
• AR
  Australian Research Council

  Award: LP150100912
• DO
  Division of Mathematical Sciences