Ethical and Safety Issues of Stem Cell-Based Therapy

Results obtained from completed and on-going clinical studies indicate huge therapeutic potential of stem cell-based therapy in the treatment of degenerative, autoimmune and genetic disorders. However, clinical application of stem cells raises numerous ethical and safety concerns. In this review, we provide an overview of the most important ethical issues in stem cell therapy, as a contribution to the controversial debate about their clinical usage in regenerative and transplantation medicine. We describe ethical challenges regarding human embryonic stem cell (hESC) research, emphasizing that ethical dilemma involving the destruction of a human embryo is a major factor that may have limited the development of…

• NS
  National Science Foundation
• SN
  Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

  Awards: MP01/12, ON175103, ON175069, IZ73Z0_152454/1, SCOPES IZ73Z0_152454/1, MP01/14
• FM
  Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu

  Awards: MP01/12, IZ73Z0_152454/1, MP01/14, ON175069, ON175103
• BA
  Biotechnology and Biological Sciences Research Council

  Awards: BB/E012841/1, BB/I020209/1