Physiology of Astroglia
Ikerbasque · University of Copenhagen · +5 more institutions
Abstract
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in morphological appearance; they express a multitude of receptors, channels, and membrane transporters. This complement underlies their remarkable adaptive plasticity that defines the functional maintenance of the CNS in development and aging. Astrocytes are tightly integrated into neural networks and act within the context of neural tissue; astrocytes control homeostasis of the CNS at all levels of organization from molecular to the whole organ.
Citation impact
- FWCI
- 47.91
- Percentile
- 100%
- References
- 1,971
Authors
2- AVAlexei VerkhratskyCorresponding
Ikerbasque, University of Copenhagen, University of the Basque Country, University of Manchester, University of Rochester Medical Center, Biomedical Research Networking Center on Neurodegenerative Diseases, Achucarro Basque Center for Neuroscience
- MNMaiken Nedergaard
Ikerbasque, University of Copenhagen, University of the Basque Country, University of Manchester, University of Rochester Medical Center, Biomedical Research Networking Center on Neurodegenerative Diseases, Achucarro Basque Center for Neuroscience
Topics & keywords
- Neuroscience
- Neuroepithelial cell
- Biology
- Context (archaeology)
- Central nervous system
- Homeostasis
- Nervous system
- Astrocyte