reviewNew England Journal of MedicineDec 28, 2017Closed access

Pathophysiology of Chronic Graft-versus-Host Disease and Therapeutic Targets

University of Freiburg · University of Minnesota

PubMed
Indexed incrossrefpubmed

Abstract

Chronic GVHD, an autoimmune disease that follows allogeneic hematopoietic-cell transplantation, is characterized by infections and debilitating tissue injury leading to irreversible fibrosis. Insights into the pathophysiology of the disease are providing new therapeutic targets.

Citation impact

718
total citations
FWCI
27.20
Percentile
100%
References
98
Citations per year

Authors

2

Topics & keywords

Keywords
  • Medicine
  • Pathophysiology
  • Disease
  • Graft-versus-host disease
  • Immunology
  • Hematopoietic stem cell transplantation
  • Transplantation
  • Fibrosis
UN Sustainable Development Goals
  • Good health and well-being
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