Bone biomaterials and interactions with stem cells
Central South University · State Key Laboratory of High Performance Complex Manufacturing · +2 more institutions
Abstract
Bone biomaterials play a vital role in bone repair by providing the necessary substrate for cell adhesion, proliferation, and differentiation and by modulating cell activity and function. In past decades, extensive efforts have been devoted to developing bone biomaterials with a focus on the following issues: (1) developing ideal biomaterials with a combination of suitable biological and mechanical properties; (2) constructing a cell microenvironment with pores ranging in size from nanoscale to submicro- and microscale; and (3) inducing the oriented differentiation of stem cells for artificial-to-biological transformation. Here we present a comprehensive review of the state of the art of bone biomaterials and…
Citation impact
- FWCI
- 27.94
- Percentile
- 100%
- References
- 429
Authors
4- CGChengde Gao
Central South University, State Key Laboratory of High Performance Complex Manufacturing
- SPShuping Peng
Central South University, Xiangya Hospital Central South University
- PFPei Feng
Central South University, State Key Laboratory of High Performance Complex Manufacturing
- CSCijun ShuaiCorresponding
Central South University, Xiangya Hospital Central South University, State Key Laboratory of High Performance Complex Manufacturing, Jiangxi University of Science and Technology
Topics & keywords
- Stem cell
- Chemistry
- Cell biology
- Biology
Funding
- NNNational Natural Science Foundation of ChinaAwards: 81572577, 2016JJ1027, 2016CX023, SKLSP201605, 51705540, BX201700291, 51575537, 81572577, 51575537
- CSCentral South UniversityAwards: 81572577, 51575537, 2016JJ1027, SKLSP201605, 2016CX023
- NSNatural Science Foundation of Hunan ProvinceAwards: 2016JJ1027, 2016CX023, SKLSP201605, 51705540, 51575537, 81572577
- SKState Key Laboratory of High Performance Complex Manufacturing
- SKState Key Laboratory of Solidification ProcessingAwards: SKLSP201605, 81572577, 2016JJ1027, 2016CX023, 51575537
- NPNational Postdoctoral Program for Innovative TalentsAward: BX201700291
- OFOpen-End Fund for the Valuable and Precision Instruments of Central South UniversityAwards: SKLSP201605, 2016CX023, 81572577, 2016JJ1027, 51575537