reviewJournal of Antimicrobial ChemotherapyNov 14, 2017BRONZE OA

Changes in the epidemiological landscape of invasive candidiasis

University of Lausanne · Centers for Disease Control and Prevention

PubMed
Indexed incrossrefpubmed

Abstract

The epidemiology of invasive candidiasis has evolved in recent years, warranting a review of the changes and the implications for current and future diagnosis and treatment. The overall burden of invasive candidiasis remains high, particularly in the expanding populations of patients at risk of opportunistic infection, such as the elderly or immunosuppressed. Progressive shifts from Candida albicans to non-albicans Candida spp. have been observed globally. The recent emergence of novel, multiresistant species, such as Candida auris, amplifies the call for vigilance in detection and advances in treatment. Among the current treatment options, fluconazole is still widely used throughout the world. Increased…

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