articleAmerican Journal of Translational ResearchJan 1, 2026GREEN OA

B7-H3 regulates migration and invasion in salivary gland adenoid cystic carcinoma via the JAK2/STAT3 signaling pathway: Am J Transl Res. 2017; 9(3): 1369-1380

TFTengfei Fan

Wuhan University

PubMed
Indexed incrossrefpubmed

Abstract

. Further mechanism studies suggested that B7-H3 influenced the migration and invasion of AdCC cells by regulating the epithelial-mesenchymal transition via JAK2/STAT3 pathway components. Collectively, these findings suggested that B7-H3 may be a potential therapeutic target for AdCC.

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Topics & keywords

Topics
Keywords
  • Antibody-dependent cell-mediated cytotoxicity
  • Adenoid cystic carcinoma
  • Immunohistochemistry
  • Gene knockdown
  • Biology
  • Cancer research
  • Salivary gland
  • Epithelial–mesenchymal transition
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