Structure–Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging
National Institutes of Health · Xiamen University · +1 more institution
Abstract
Magnetic nanoparticles (MNPs) have been extensively explored as magnetic resonance imaging (MRI) contrast agents. With the increasing complexity in the structure of modern MNPs, the classical Solomon-Bloembergen-Morgan and the outer-sphere quantum mechanical theories established on simplistic models have encountered limitations for defining the emergent phenomena of relaxation enhancement in MRI. Recent progress in probing MRI relaxivity of MNPs based on structural features at the molecular and atomic scales is reviewed, namely, the structure-relaxivity relationships, including size, shape, crystal structure, surface modification, and assembled structure. A special emphasis is placed on bridging the gaps…
Citation impact
- FWCI
- 20.19
- Percentile
- 100%
- References
- 363
Authors
4- ZZZijian Zhou
National Institutes of Health, Xiamen University, National Institute of Biomedical Imaging and Bioengineering
- LYLijiao Yang
Xiamen University
- JGJinhao GaoCorresponding
Xiamen University
- XCXiaoyuan ChenCorresponding
National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering
Topics & keywords
- Magnetic resonance imaging
- Materials science
- Magnetic nanoparticles
- Nanoparticle
- Nanotechnology
- Relaxation (psychology)
- Nuclear magnetic resonance
- Chemical physics