A comprehensive review on tyrosinase inhibitors

Islamic Azad University, Jahrom Branch · General Dynamics (United States) · +3 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning. Therefore, its inhibitors can be attractive in cosmetics and medicinal industries as depigmentation agents and also in food and agriculture industries as antibrowning compounds. For this purpose, many natural, semi-synthetic and synthetic inhibitors have been developed by different screening methods to date. This review has focused on the tyrosinase inhibitors discovered from all sources and biochemically characterised in the last four decades.

Citation impact

1,023
total citations
FWCI
55.72
Percentile
100%
References
443
Citations per year

Authors

7

Topics & keywords

Keywords
  • Tyrosinase
  • Depigmentation
  • Cosmetics
  • Browning
  • Chemistry
  • Enzyme
  • Biochemistry
  • Biotechnology
UN Sustainable Development Goals
  • Zero hunger
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