Depression in sleep disturbance: A review on a bidirectional relationship, mechanisms and treatment
First Affiliated Hospital Zhejiang University · State Key Laboratory of Diagnosis and Treatment of Infectious Diseases · +2 more institutions
Abstract
Sleep disturbance is the most prominent symptom in depressive patients and was formerly regarded as a main secondary manifestation of depression. However, many longitudinal studies have identified insomnia as an independent risk factor for the development of emerging or recurrent depression among young, middle-aged and older adults. This bidirectional association between sleep disturbance and depression has created a new perspective that sleep problems are no longer an epiphenomenon of depression but a predictive prodromal symptom. In this review, we highlight the treatment of sleep disturbance before, during and after depression, which probably plays an important role in improving outcomes and preventing the…
Citation impact
- FWCI
- 69.73
- Percentile
- 100%
- References
- 123
Authors
4- HFHong Fang
First Affiliated Hospital Zhejiang University, State Key Laboratory of Diagnosis and Treatment of Infectious Diseases, Zhejiang University
- STSheng Tu
First Affiliated Hospital Zhejiang University, State Key Laboratory of Diagnosis and Treatment of Infectious Diseases, Zhejiang University
- JSJifang ShengCorresponding
First Affiliated Hospital Zhejiang University, State Key Laboratory of Diagnosis and Treatment of Infectious Diseases, Zhejiang University
- ASAnwen ShaoCorresponding
Second Affiliated Hospital of Zhejiang University
Topics & keywords
- Depression (economics)
- Sleep disorder
- Comorbidity
- Epiphenomenon
- Insomnia
- Disturbance (geology)
- Psychiatry
- Psychology
- Good health and well-being