Highly efficient photothermal nanoagent achieved by harvesting energy via excited-state intramolecular motion within nanoparticles
Hong Kong University of Science and Technology · Institute of Molecular Functional Materials · +6 more institutions
Abstract
The exciting applications of molecular motion are still limited and are in urgent pursuit, although some fascinating concepts such as molecular motors and molecular machines have been proposed for years. Utilizing molecular motion in a nanoplatform for practical application has been scarcely explored due to some unconquered challenges such as how to achieve effective molecular motion in the aggregate state within nanoparticles. Here, we introduce a class of near infrared-absorbing organic molecules with intramolecular motion-induced photothermy inside nanoparticles, which enables most absorbed light energy to dissipate as heat. Such a property makes the nanoparticles a superior photoacoustic imaging agent…
Citation impact
- FWCI
- 24.41
- Percentile
- 100%
- References
- 58
Authors
16- ZZZheng ZhaoCorresponding
Hong Kong University of Science and Technology, Institute of Molecular Functional Materials, University of Hong Kong
- CCChao Chen
Nankai University, State Key Laboratory of Medicinal Chemical Biology
- WWWenting Wu
Shanghai Institute of Organic Chemistry
- FWFenfen Wang
Nankai University
- LDLili Du
Jiangsu University, University of Hong Kong
Topics & keywords
- Nanoparticle
- Photothermal therapy
- Intramolecular force
- Materials science
- Molecular imaging
- Nanotechnology
- Photoacoustic imaging in biomedicine
- Molecular motor
- Affordable and clean energy
Funding
- NSNational Science Foundation
- NNNational Natural Science Foundation of ChinaAwards: 21788102, ITC-CNERC14SC01, 51873092, 16308016, 16305015, C6009-17G, 51622305
- IAInnovation and Technology CommissionAwards: ITC-CNERC14SC01 and ITS/254/17, ITS/254/17, CNERC14SC01, ITC-CNERC14SC01
- HKHong Kong University of Science and Technology
- NKNational Key Research and Development Program of ChinaAwards: 2015CB856503, 21788102