reviewChemical ReviewsFeb 13, 2019HYBRID OA

Emerging Diversity in Lipid–Protein Interactions

University of Calgary · University of Groningen

PubMed
Indexed incrossrefpubmed

Abstract

Membrane lipids interact with proteins in a variety of ways, ranging from providing a stable membrane environment for proteins to being embedded in to detailed roles in complicated and well-regulated protein functions. Experimental and computational advances are converging in a rapidly expanding research area of lipid-protein interactions. Experimentally, the database of high-resolution membrane protein structures is growing, as are capabilities to identify the complex lipid composition of different membranes, to probe the challenging time and length scales of lipid-protein interactions, and to link lipid-protein interactions to protein function in a variety of proteins. Computationally, more accurate membrane…

Citation impact

500
total citations
FWCI
21.27
Percentile
100%
References
848
Citations per year

Authors

7

Topics & keywords

Keywords
  • Chemistry
  • Protein–protein interaction
  • Computational biology
  • Function (biology)
  • Membrane protein
  • Nanotechnology
  • Biophysics
  • Membrane
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