First Human Imaging Studies with the EXPLORER Total-Body PET Scanner*

Within the EXPLORER Consortium, the construction of the world’s first total-body PET/CT scanner has recently been completed. The 194-cm axial field of view of the EXPLORER PET/CT scanner is sufficient to cover, for the first time, the entire human adult body in a single acquisition in more than 99% of the population and allows total-body pharmacokinetic studies with frame durations as short as 1 s. The large increase in sensitivity arising from total-body coverage as well as increased solid angle for detection at any point within the body allows whole-body 18F-FDG PET studies to be acquired with unprecedented count density, improving the signal-to-noise ratio of the resulting images. Alternatively, the…

• UO
  University of Pennsylvania
• UO
  University of California, Davis
• NO
  NIH Office of the Director
• NC
  National Cancer Institute
• NI
  National Institute of Biomedical Imaging and Bioengineering