reviewPharmaceuticsJan 29, 2019GOLD OA

Advances of Non-Ionic Surfactant Vesicles (Niosomes) and Their Application in Drug Delivery

Nanjing Forestry University · Shanghai Jiao Tong University · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Non-Ionic surfactant based vesicles, also known as niosomes, have attracted much attention in pharmaceutical fields due to their excellent behavior in encapsulating both hydrophilic and hydrophobic agents. In recent years, it has been discovered that these vesicles can improve the bioavailability of drugs, and may function as a new strategy for delivering several typical of therapeutic agents, such as chemical drugs, protein drugs and gene materials with low toxicity and desired targeting efficiency. Compared with liposomes, niosomes are much more stable during the formulation process and storage. The required pharmacokinetic properties can be achieved by optimizing components or by surface modification. This…

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551
total citations
FWCI
20.26
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100%
References
93
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Authors

4

Topics & keywords

Keywords
  • Niosome
  • Bioavailability
  • Pulmonary surfactant
  • Drug delivery
  • Vesicle
  • Nanotechnology
  • Liposome
  • Drug
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